ultima modifica 28/11/2013 17:26


Mallei A, Baj G,  Ieraci A, Corna S, Musazzi L, Lee FS, Tongiorgi E, Popoli M. (2015) Expression and dendritic trafficking of BDNF-6 splice variant are impaired in knock-in mice carrying human BDNF Val66Met polymorphism. International J. Neuropsychopharmacology (in press)

Ieraci A, Mallei A, Musazzi L, Popoli M. (2015) Physical exercise and acute restraint stress differentially modulate hippocampal brain-derived neurotrophic factor transcripts and epigenetic mechanisms in mice. Hippocampus. 2015 Mar 26.

Tardito D, Mallei A, Popoli M. (2013) Lost in translation. New unexplored avenues for neuropsychopharmacology: epigenetics and microRNAs. Exp Opin Invest Drugs 22:217-33.

Baj G, D’Alessandro V, Musazzi L, Mallei A, Tardito D, Sartori CR, Sciancalepore M, Langone F, Popoli M, Tongiorgi E. (2012) Physical exercise and antidepressants enhance BDNF targeting in hippocampal CA3 dendrites: further evidence of a spatial code for BDNF splice variants. Neuropsychopharmacol 37:1600-11.

Popoli M, Yan Z, McEwen BS, Sanacora G. (2012) The stressed synapse: the impact of behavioral stress and glucocorticoids on glutamate transmission. Nature Rev Neurosci 13:22-37.

Musazzi L, Milanese M, Barbiero VS, Zappettini S, Tardito D, Farisello P, Bonifacino T, Mallei A, Baldelli P, Racagni G, Raiteri M, Benfenati F, Bonanno G, Popoli M. (2010) Acute stress increases depolarization-evoked glutamate release in the rat prefrontal/frontal cortex. The dampening action of antidepressants. PloS ONE 5(1):e8566.

Musazzi L, Cattaneo A, Tardito D, Barbon A, Gennarelli M, Barlati S, Racagni G, Popoli M. (2009) Early raise of BDNF in hippocampus suggests induction of posttranscriptional mechanisms by antidepressants. BMC Neuroscience 10:48



Sgadò P, Genovesi S, Kalinovsky A, Zunino G, Macchi F, Allegra M, Murenu E, Provenzano G, Tripathi PP, Casarosa S, Joyner AL, Bozzi Y. (2013)  Loss of GABAergic neurons in the hippocampus and cerebral cortex of Engrailed-2 null mutant mice: Implications for autism spectrum disorders. Exp Neurol. Jan 26. 2013

Provenzano G., Zunino G., Genovesi S., Sgadò P., Bozzi Y. (2012) Mutant mouse models of autism spectrum disorders. Disease Markers 33;225-239

Sgadò P, Dunleavy M, Genovesi S, Provenzano G, Bozzi Y (2011) The role of GABAergic system in neurodevelopmental disorders: a focus on autism and epilepsy. Int J Physiol Pathophysiol Pharmacol 3:223-235.

Tripathi PP, Sgadò P, Scali M, Viaggi C, Casarosa S, Simon H, Vaglini F, Corsini GU, Bozzi Y (2009) Increased susceptibility to kainic acid-induced seizures in Engrailed-2 knockout mice. Neuroscience 159:842-9.



Paradiso B, Zucchini S, Simonato M. Implication of fibroblast growth factors in epileptogenesis-associated circuit rearrangements. Front Cell Neurosci. 2013 Sep 13;7:152. Review.

O'Brien TJ, Ben-Menachem E, Bertram EH 3rd, Collins SD, Kokaia M, Lerche H, Klitgaard H, Staley KJ, Vaudano E, Walker MC, Simonato M. Proposal for a "phase II" multicenter trial model for preclinical new antiepilepsy therapy development. Epilepsia. 2013 Aug;54 Suppl 4:70-4. Review

Galanopoulou AS, Simonato M, French JA, O'Brien TJ. Joint AES/ILAE translational workshop to optimize preclinical epilepsy research. Epilepsia. 2013 Aug;54 Suppl 4:1-2.

Simonato M, Bennett J, Boulis NM, Castro MG, Fink DJ, Goins WF, Gray SJ, Lowenstein PR, Vandenberghe LH, Wilson TJ, Wolfe JH, Glorioso JC Progress in gene therapy for neurological disorders. Nat Rev Neurol. 2013 May;9(5):277-91

Su T, Scardigli R, Fasulo L, Paradiso B, Barbieri M, Binaschi A, Bovolenta R, Zucchini S, Cossu G, Cattaneo A, Simonato M. Bystander effect on brain tissue of mesoangioblasts producing neurotrophins. Cell Transplant. 2012;21(8):1613-27.

Paradiso B, Zucchini S, Su T, Bovolenta R, Berto E, Marconi P, Marzola A, Navarro Mora G, Fabene PF, Simonato M. Localized overexpression of FGF-2 and BDNF in hippocampus reduces mossy fiber sprouting and spontaneous seizures up to 4 weeks after pilocarpine-induced status epilepticus. Epilepsia. 2011 Mar;52(3):572-8.


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Project coordinator: prof. Michele Simonato -